Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph

CAT:

804-HY-163826

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UNSPSC Description: Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph is a ligand for E3 ubiquitin ligase. Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph can be connected to the ligand for protein by a linker to form 22-SLF (HY-163807)[1].
Target Antigen: Ligands for E3 Ligase
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/benzothiazole-ch2-nh-co-ch2cl-conh-ch2-ph.html
Smiles: O=C(CCl)NC(C1=NC2=C(S1)C=CC=C2)C(NCC3=CC=CC=C3)=O
Molecular Weight: 373.86
References & Citations: [1]Ananya A Basu, A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation. bioRxiv[Preprint]. 2023 Sep 16:2023.09.15.557708.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-163826	Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph
HY-159077	H2N-C6-NH-CO-CH2-O-Ph-CH2-NH-Boc
HY-168291	Thalidomide-NH-CH2-CONH-C6-Br
HY-164593	NH-CH2-CH2-DOTAM
HY-W584525	VH032-NH-CO-CH2-NHBoc
HY-169397	Thalidomide-NH-CH2-CONH-C2-PEG-bromine
HY-157813-02	2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan
HY-157813-01	2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan
HY-46346-05	Fmoc-Gly-NH-CH2-O-CH2-Cbz
HY-46346-04	Fmoc-Gly-NH-CH2-O-CH2-Cbz

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