2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan

• CAS Number: 2964536-59-0
• UNSPSC Description: 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugates for ADC, consiting of a cleavable linker and Exatecan (HY-13631). 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan can be linked to anti-Her3 antibody[1].
• Target Antigen: Drug-Linker Conjugates for ADC; Topoisomerase
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-msp-5-ha-ggfg-nh-ch2-o-ch2-co-exatecan.html
• Solubility: DMSO : 200 mg/mL (ultrasonic)
• Smiles: CS(C1=NC=C(C=N1)C#CCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)(=O)=O
• Molecular Weight: 1091.13
• References & Citations: [1]Cai JQ, et al. Antibody against her3, conjugate and use thereof. WO2023143263A1. 2023-08-03.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported