Thalidomide-NH-CH2-CONH-C2-PEG-bromine

CAT:

804-HY-169397

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UNSPSC Description: Thalidomide-NH-CH2-CONH-C2-PEG-bromine is a conjugate of the E3 ligase ligand and the linker, that can be used for synthesis of PROTAC degrader SK-3-91 (HY-137341)[1].
Target Antigen: E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-nh-ch2-conh-c2-peg-bromine.html
Smiles: O=C(N1C2C(NC(CC2)=O)=O)C3=C(NCC(NCCOCCBr)=O)C=CC=C3C1=O
Molecular Weight: 481.30
References & Citations: [1]Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183(6):1714-1731.e10.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-169397	Thalidomide-NH-CH2-CONH-C2-PEG-bromine
HY-168291	Thalidomide-NH-CH2-CONH-C6-Br
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HY-131717-02	Thalidomide-NH-CH2-COOH
HY-131717-01	Thalidomide-NH-CH2-COOH
HY-163826	Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph
HY-W584513	Thalidomide-NH-(CH2)2-NH-Boc
HY-W584515	Thalidomide-NH-(CH2)3-NH-Boc
HY-131717A	Thalidomide-NH-CH2-COOH (TFA)
HY-145177-03	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc