Estradiol

• Description :

  Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2].

• Product Name Alternative :

  β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol

• UNSPSC :

  12352005

• Hazard Statement :

  H351, H360, H362, H410

• Target :

  Bacterial; Endogenous Metabolite; Estrogen Receptor/ERR

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Endocrinology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Estradiol.html

• Purity :

  99.93

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |Ethanol : 16.67 mg/mL (ultrasonic)

• Smiles :

  C[C@@]1([C@H]2O)[C@](CC2)([H])[C@@](CCC3=C4C=CC(O)=C3)([H])[C@]4([H])CC1

• Molecular Formula :

  C18H24O2

• Molecular Weight :

  272.39

• Precautions :

  H351, H360, H362, H410

• References & Citations :

  [1]Elham Hasanzadeh. Defining the role of 17β-estradiol in human endometrial stem cells differentiation into neuron-like cells. Cell Biol Int. 2021 Jan;45 (1) :140-153. |[2]Yujiao Lu, et al. Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory. J Neurosci. 2019 Apr 10;39 (15) :2792-2809.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [50-28-2]