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Estriol-13C3

CAT: 0804-HY-B0412S3Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0412S3Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Estriol-13C3 is the 13C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.
CAS Number
1255639-56-5
Product Name Alternative
Oestriol-13C3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite; Estrogen Receptor/ERR; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/estriol-13c3.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C[C@H]([C@@H]2O)O)([H])[C@@]3([H])[C@@](CC1)([H])C4=C[13CH]=[13C](O)[13CH]=C4CC3
Molecular Formula
C15 13C3H24O3
Molecular Weight
291.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Morinaga, A., et al., Effects of sex hormones on Alzheimer's disease-associated beta-amyloid oligomer formation in vitro. Exp Neurol, 2011. 228 (2) : p. 298-302.|[3]Begum, M., et al., Neonatal estrogenic exposure suppresses PTEN-related endometrial carcinogenesis in recombinant mice. Lab Invest, 2006. 86 (3) : p. 286-96.|[4]Hewitt, S.C. and K.S. Korach, Estrogenic activity of bisphenol A and 2,2-bis (p-hydroxyphenyl) -1,1,1-trichloroethane (HPTE) demonstrated in mouse uterine gene profiles. Environ Health Perspect, 2011. 119 (1) : p. 63-70.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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