SUMO2 Rabbit pAb

CAT:
855-ES12884-01
Size:
50 µL
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
SUMO2 Rabbit pAb - image 1

SUMO2 Rabbit pAb

  • Background:

    This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Description:

    This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
  • Synonyms:

    Small ubiquitin-related modifier 2 (SUMO-2;HSMT3;SMT3 homolog 2;SUMO-3;Sentrin-2;Ubiquitin-like protein SMT3A;Smt3A)
  • Gene ID:

    6613
  • UniProt:

    P61956
  • Cellular Locus:

    Nucleus. Nucleus, PML body.
  • Host:

    Rabbit
  • Species Reactivity:

    Human, Mouse, Rat
  • Reactivity:

    Human; Mouse; Rat
  • Immunogen:

    Synthesized peptide derived from human SUMO2 AA range: 45-95
  • Clonality:

    Polyclonal
  • Isotype:

    IgG
  • Source:

    Rabbit
  • Applications:

    WB, IHC, IF, ELISA
  • Validated Applications:

    WB, IHC, IF, ELISA
  • Stability:

    -20°C/1 year
  • Concentration:

    1 mg/mL
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
  • Storage Conditions:

    PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
  • Subcellular Location:

    Nucleus. Nucleus, PML body.
  • Other Product Names:

    Small ubiquitin-related modifier 2 (SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3A; Smt3A)
  • Gene ID (Human):

    6613
  • SwissProt (Human):

    P61956