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CASP7 antibody

CAT: 0710-FNab10124Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10124Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
Caspase-7 (CASP-7) |Apoptotic protease Mch-3|CMH-1|ICE-like apoptotic protease 3 (ICE-LAP3) |Caspase-7 subunit p20|Caspase-7 subunit p11|CASP7|MCH3
Gene ID
840
UniProt
P55210
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Caspase-7
Target
CASP7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
37 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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