CASP7 antibody

• Background :

  This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Synonyms :

  Caspase-7 (CASP-7) |Apoptotic protease Mch-3|CMH-1|ICE-like apoptotic protease 3 (ICE-LAP3) |Caspase-7 subunit p20|Caspase-7 subunit p11|CASP7|MCH3

• Gene ID :

  840

• UniProt :

  P55210

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Caspase-7

• Target :

  CASP7

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Cancer, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  37 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF