MAP2K4 antibody

CAT: 0710-FNab10073Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab10073Size:100 µg
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Background
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Synonyms
Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4, MAPKK 4) |JNK-activating kinase 1|MAPK/ERK kinase 4 (MEK 4) |SAPK/ERK kinase 1 (SEK1) |Stress-activated protein kinase kinase 1 (SAPK kinase 1, SAPKK-1, SAPKK1) |c-Jun N-terminal kinase kinase 1 (JNKK) |MAP2K4|JNKK1|MEK4|MKK4|PRKMK4|SEK1|SERK1|SKK1
Gene ID
6416
UniProt
P45985
Host
Rabbit
Reactivity
Human, mouse, Rat
Immunogen
MAP2K4
Target
MAP2K4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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