MAP2K1 antibody

• Background :

  MEK1 is also named as MAP2K1 (mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling (PMID:19219045) . It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated.

• Synonyms :

  Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1, MAPKK 1, MKK1) |ERK activator kinase 1|MAPK/ERK kinase 1 (MEK 1) |MAP2K1|MEK1|PRKMK1

• Gene ID :

  5604

• UniProt :

  Q02750

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Mitogen-activated protein kinase kinase 1

• Target :

  MAP2K1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Immunology, Signal Transduction, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:50-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  40 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF