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MAP2K1 antibody

CAT: 0710-FNab05112Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05112Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MEK1 is also named as MAP2K1 (mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling (PMID:19219045) . It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated.
Synonyms
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1, MAPKK 1, MKK1) |ERK activator kinase 1|MAPK/ERK kinase 1 (MEK 1) |MAP2K1|MEK1|PRKMK1
Gene ID
5604
UniProt
Q02750
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mitogen-activated protein kinase kinase 1
Target
MAP2K1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Immunology, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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