MAP2K6 antibody

• Background:

  This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

• Synonyms:

  Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6, MAPKK 6) |MAPK/ERK kinase 6 (MEK 6) |Stress-activated protein kinase kinase 3 (SAPK kinase 3, SAPKK-3, SAPKK3) |MAP2K6|MEK6|MKK6|PRKMK6|SKK3

• Gene ID:

  5608

• UniProt:

  P52564

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Mitogen-activated protein kinase kinase 6

• Target:

  MAP2K6

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, FC

• Field of Research:

  Stem Cells, Immunology, Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2400; IHC: 1:50-1:500

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  37 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, FC