MAP2K5 antibody

• Background:

  The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

• Synonyms:

  Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5, MAPKK 5) |MAPK/ERK kinase 5 (MEK 5) |MAP2K5|MEK5|MKK5|PRKMK5

• Gene ID:

  5607

• UniProt:

  Q13163

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Mitogen-activated protein kinase kinase 5

• Target:

  MAP2K5

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Cardiovascular, Metabolism, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  50 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF