MAP2K5 antibody

CAT: 0710-FNab05117Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab05117Size:100 µg
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Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Synonyms
Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5, MAPKK 5) |MAPK/ERK kinase 5 (MEK 5) |MAP2K5|MEK5|MKK5|PRKMK5
Gene ID
5607
UniProt
Q13163
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mitogen-activated protein kinase kinase 5
Target
MAP2K5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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