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SNCB antibody

CAT: 0710-FNab10048Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10048Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA) -stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Synonyms
Beta-synuclein|SNCB|SYUB
Gene ID
6620
UniProt
Q16143
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synuclein, beta
Target
SNCB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
14-18 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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