SNCA antibody
CAT:
710-FNab09891
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SNCA antibody
- Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
- Synonyms: Alpha-synuclein|Non-A beta component of AD amyloid|Non-A4 component of amyloid precursor (NACP)|SNCA|NACP|PARK1
- CAS Number: 9007-83-4
- Gene ID: 6622
- UniProt: P37840
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Immunogen: synuclein, alpha (non A4 component of amyloid precursor)
- Target: SNCA
- Clonality: Monoclonal
- Isotype: IgG1
- Clone: 5C6
- Applications: ELISA, IHC, WB
- Field of Research: Neuroscience
- Purification: protein A+G purified
- Dilution: WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 18 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)