TRAF7 antibody

• Background:

  E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed.

• Synonyms:

  E3 ubiquitin-protein ligase TRAF7|RING finger and WD repeat-containing protein 1|RING finger protein 119|RING-type E3 ubiquitin transferase TRAF7|TNF receptor-associated factor 7|TRAF7|RFWD1|RNF119

• Gene ID:

  84231

• UniProt:

  Q6Q0C0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  TNF receptor-associated factor 7

• Target:

  TRAF7

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, IP, WB

• Field of Research:

  Epigenetics, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  67-75 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, IP, WB