TRAF1 antibody

• Background:

  Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

• Synonyms:

  TNF receptor-associated factor 1|Epstein-Barr virus-induced protein 6|TRAF1|EBI6

• Gene ID:

  26146

• UniProt:

  Q13077

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  TNF receptor-associated factor 1

• Target:

  TRAF1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC

• Field of Research:

  Immunology, Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  46 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC