TRAF4 antibody

CAT: 0710-FNab08919Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab08919Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P) H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

Synonyms

Gene ID

9618

UniProt

Q9BUZ4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

TNF receptor-associated factor 4

Target

TRAF4

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Stem Cells, Signal Transduction, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

54 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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