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TNFAIP1 antibody

CAT: 0710-FNab08817Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08817Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR (BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Synonyms
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) |BTB/POZ domain-containing protein TNFAIP1|Protein B12|Tumor necrosis factor, alpha-induced protein 1, endothelial|TNFAIP1|BACURD2|EDP1
Gene ID
7126
UniProt
Q13829
Host
Mouse
Reactivity
Human
Immunogen
Tumor necrosis factor, alpha-induced protein 1 (endothelial)
Target
TNFAIP1
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:6000; IHC: 1:50-1:600
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2H3
Tested Applications
ELISA, WB, IHC

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