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TNFAIP8 antibody

CAT: 0710-FNab08819Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08819Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Synonyms
Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8) |Head and neck tumor and metastasis-related protein|MDC-3.13|NF-kappa-B-inducible DED-containing protein (NDED) |SCC-S2|TNF-induced protein GG2-1|TNFAIP8
Gene ID
25816
UniProt
O95379
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tumor necrosis factor, alpha-induced protein 8
Target
TNFAIP8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21-23 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · O95379

Tumor necrosis factor alpha-induced protein 8

TFIP8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95379
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNFAIP8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TNF alpha-induced protein 8
EC number
—
Processing
—
Secondary accessions
B3KMH1, B3KMI2, B7Z713, Q9P1Q1, Q9UER5, Q9UP47
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Domain

Coiled coil

Cellular component

Cytoplasm

Technical term

Proteomics identificationReference proteome

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MBS8576507-01TNFAIP8 Antibody

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