STK3 antibody

CAT: 0710-FNab08329Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab08329Size:100 µg
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Background
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
Serine/threonine-protein kinase 3|Mammalian STE20-like protein kinase 2 (MST-2) |STE20-like kinase MST2|Serine/threonine-protein kinase Krs-1|Serine/threonine-protein kinase 3 36kDa subunit (MST2/N) |Serine/threonine-protein kinase 3 20kDa subunit (MST2/C) |STK3|KRS1|MST2
Gene ID
6788
UniProt
Q13188
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Serine/threonine kinase 3 (STE20 homolog, yeast)
Target
STK3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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