STK3 antibody

• Background:

  This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  Serine/threonine-protein kinase 3|Mammalian STE20-like protein kinase 2 (MST-2) |STE20-like kinase MST2|Serine/threonine-protein kinase Krs-1|Serine/threonine-protein kinase 3 36kDa subunit (MST2/N) |Serine/threonine-protein kinase 3 20kDa subunit (MST2/C) |STK3|KRS1|MST2

• Gene ID:

  6788

• UniProt:

  Q13188

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Serine/threonine kinase 3 (STE20 homolog, yeast)

• Target:

  STK3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  60 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC