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STK4 antibody

CAT: 0710-FNab08339Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08339Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Synonyms
Serine/threonine-protein kinase 4|Mammalian STE20-like protein kinase 1 (MST-1) |STE20-like kinase MST1|Serine/threonine-protein kinase Krs-2|Serine/threonine-protein kinase 4 37kDa subunit (MST1/N) |Serine/threonine-protein kinase 4 18kDa subunit (MST1/C) |STK4|KRS2|MST1
Gene ID
6789
UniProt
Q13043
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Serine/threonine kinase 4
Target
STK4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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