SMARCB1 antibody

• Background:

  The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.

• Synonyms:

  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1|BRG1-associated factor 47 (BAF47) |Integrase interactor 1 protein|SNF5 homolog (hSNF5) |SMARCB1|BAF47|INI1|SNF5L1

• Gene ID:

  6598

• UniProt:

  Q12824

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

• Target:

  SMARCB1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Immunology, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  44 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC