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SMARCA1 antibody

CAT: 0710-FNab10936Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10936Size:100 µg
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Background
This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants.
Synonyms
Probable global transcription activator SNF2L1|ATP-dependent helicase SMARCA1|Nucleosome-remodeling factor subunit SNF2L|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1|SMARCA1|SNF2L|SNF2L1
UniProt
P28370
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
Target
SMARCA1
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
WB

UniProtKB · P28370

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

SMCA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P28370
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SMARCA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SMARCA1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A1
EC number
3.6.4.-
Processing
—
Secondary accessions
Q5JV41, Q5JV42
Protein keywords

Molecular function

ActivatorChromatin regulatorHydrolase

Coding sequence diversity

Alternative splicing

Cellular component

ChromosomeNucleus

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Technical term

Proteomics identificationReference proteome

Domain

Repeat

Biological process

TranscriptionTranscription regulation

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