SMARCA4 antibody

CAT: 0710-FNab08004Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab08004Size:100 µg
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Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
Transcription activator BRG1|ATP-dependent helicase SMARCA4|BRG1-associated factor 190A (BAF190A) |Mitotic growth and transcription activator|Protein BRG-1|Protein brahma homolog 1|SNF2-beta|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4|SMARCA4|BAF190A|BRG1|SNF2B|SNF2L4
Gene ID
6597
UniProt
P51532
Host
Rabbit
Reactivity
Human
Immunogen
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Target
SMARCA4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Epigenetics, Stem Cells, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
180 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
30-130aa

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