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SERPIND1 antibody

CAT: 0710-FNab07750Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07750Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III) . Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
Synonyms
Heparin cofactor 2|Heparin cofactor II (HC-II) |Protease inhibitor leuserpin-2 (HLS2) |Serpin D1|SERPIND1|HCF2
Gene ID
3053
UniProt
P05546
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Target
SERPIND1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57-60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC