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RNF6 antibody

CAT: 0710-FNab07360Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07360Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Synonyms
E3 ubiquitin-protein ligase RNF6|RNF6|SPG2
Gene ID
6049
UniProt
Q9Y252
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Ring finger protein (C3H2C3 type) 6
Target
RNF6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Epigenetics, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
78 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

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