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RNF7 antibody

CAT: 0710-FNab07361Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07361Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
Synonyms
RING-box protein 2 (Rbx2) |CKII beta-binding protein 1 (CKBBP1) |RING finger protein 7|Regulator of cullins 2|Sensitive to apoptosis gene protein|RNF7|RBX2|ROC2|SAG
Gene ID
9616
UniProt
Q9UBF6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ring finger protein 7
Target
RNF7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
13 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

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