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MGAT4C antibody

CAT: 0710-FNab05160Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05160Size:100 µg
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Background
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri-and tetra-antennary N-linked sugar chains (By similarity) . Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity) .
Synonyms
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C|N-acetylglucosaminyltransferase IV homolog (hGnT-IV-H) |N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc (GlcNAc-T IVc, GnT-IVc, N-acetylglucosaminyltransferase IVc) |UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc|MGAT4C
Gene ID
25834
UniProt
Q9UBM8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mannosyl (alpha-1,3-) -glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
Target
MGAT4C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · Q9UBM8

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

MGT4C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UBM8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MGAT4C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.1.145
Processing
—
Secondary accessions
B4DRH2, Q4G199, Q9UIU5
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Glycoprotein

Molecular function

GlycosyltransferaseTransferase

Cellular component

Golgi apparatusMembrane

Ligand

Metal-binding

Technical term

Proteomics identificationReference proteome

Domain

Signal-anchorTransmembraneTransmembrane helix

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