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MGAT1 antibody

CAT: 0710-FNab05156Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05156Size:100 µg
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Background
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1, 2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.
Synonyms
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I (GNT-I, GlcNAc-T I) |MGAT1|GGNT1|GLCT1|GLYT1|MGAT
Gene ID
4245
UniProt
P26572
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mannosyl (alpha-1, 3-) -glycoprotein beta-1, 2-N-acetylglucosaminyltransferase
Target
MGAT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P26572

Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

MGAT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26572
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MGAT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.1.101
Processing
—
Secondary accessions
A8K404, B3KRU8, D3DWR1, Q6IBE3
Protein keywords

Cellular component

CytoplasmGolgi apparatusMembrane

PTM

Disulfide bond

Molecular function

GlycosyltransferaseTransferase

Ligand

ManganeseMetal-binding

Technical term

Proteomics identificationReference proteome

Domain

Signal-anchorTransmembraneTransmembrane helix

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