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HSD17B6 antibody

CAT: 0710-FNab04027Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04027Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro) . Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro) . Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro) . Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro) . Has retinol dehydrogenase activity towards all-trans-retinol (in vitro) . Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
Synonyms
17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6, 17-beta-HSD6) |3-alpha->beta-hydroxysteroid epimerase (3-alpha->beta-HSE) |Oxidative 3-alpha hydroxysteroid dehydrogenase|Short chain dehydrogenase/reductase family 9C member 6|HSD17B6|RODH|SDR9C6
Gene ID
8630
UniProt
O14756
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Hydroxysteroid (17-beta) dehydrogenase 6 homolog (Mouse)
Target
HSD17B6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33-35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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