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CYP27A1 antibody

CAT: 0710-FNab02153Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02153Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Synonyms
Sterol 26-hydroxylase, mitochondrial|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase|Cytochrome P-450C27/25|Cytochrome P450 27|Sterol 27-hydroxylase|Vitamin D (3) 25-hydroxylase|CYP27A1|CYP27
Gene ID
1593
UniProt
Q02318
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Cytochrome P450, family 27, subfamily A, polypeptide 1
Target
CYP27A1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

UniProtKB · Q02318

Sterol 26-hydroxylase, mitochondrial

CP27A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02318
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP27A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.15.15
Processing
Precursor
Secondary accessions
A8K303, Q6LDB4, Q86YQ6
Protein keywords

PTM

Acetylation

Disease

CataractDisease variant

Biological process

Cholesterol metabolismLipid biosynthesisLipid metabolismSteroid biosynthesisSteroid metabolismSterol metabolism

Ligand

HemeIronMetal-binding

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Molecular function

MonooxygenaseOxidoreductase

Technical term

Proteomics identificationReference proteome

Domain

Transit peptide

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