CYP24A1 antibody

• Background:

  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial (24-OHase, Vitamin D (3) 24-hydroxylase) |Cytochrome P450 24A1|Cytochrome P450-CC24|CYP24A1|CYP24

• Gene ID:

  1591

• UniProt:

  Q07973

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Cytochrome P450, family 24, subfamily A, polypeptide 1

• Target:

  CYP24A1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  59 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC