PROTAC eDHFR Degrader-1

PROTAC eDHFR Degrader-1

• CAS Number: 2849442-92-6
• UNSPSC Description: PROTAC eDHFR Degrader-1 is a PROTAC that is effective degradation of eDHFR-YFP, various POIs-including YFP and Luciferase[1].
• Target Antigen: PROTACs
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/protac-edhfr-degrader-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: NC1=C(CC2=CC(OC)=C(OCCCC(NCCOCCOCCNC3=CC=CC(C(N4C5CCC(NC5=O)=O)=O)=C3C4=O)=O)C(OC)=C2)C=NC(N)=N1
• Molecular Weight: 748.78
• References & Citations: [1]Jean M. Etersque, Regulation of eDHFR-tagged proteins with trimethoprim PROTACs.Nat Commun. 2023; 14: 7071.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported