PROTAC ERα Degrader-1

PROTAC ERα Degrader-1

• CAS Number: 2417369-94-7
• UNSPSC Description: PROTAC ERα Degrader-1 comprises an ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Degrader-1 extracts from patent WO2017201449A1, compound P1. PROTAC ERα Degrader-1 is an estrogen receptor-alpha (ERα) degrader.
• Target Antigen: Estrogen Receptor/ERR; PROTACs
• Type: Reference compound
• Related Pathways: PROTAC;Vitamin D Related/Nuclear Receptor
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/PROTAC_15.html
• Purity: 96.68
• Solubility: DMSO : 200 mg/mL (ultrasonic)
• Smiles: OC1=CC=C(/C(C2=CC=C(OCCN(C)C(COCCOCCNC(C3=CC=C(C(N4[C@@H](C)[C@H](NC([C@H](C)NC)=O)C(N(CC5=C(OC)C=CC6=C5C=CC=C6)C7=C4C=C(C#N)C=C7)=O)=O)C=C3)=O)=O)C=C2)=C(C8=CC=CC=C8)\CC)C=C1
• Molecular Weight: 1120.29
• References & Citations: [1]Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, stored under nitrogen)
• Clinical Information: No Development Reported