Hsp110-STAT3 interaction-IN-1

Hsp110-STAT3 interaction-IN-1

• CAS Number: 882582-26-5
• UNSPSC Description: Row174336 (compound 29) is a potent inhibitor of Hsp110-STAT3 interaction that shows antiproliferative activity against HPAEC cell line, with the IC50 of 22.67 μM[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/hsp110-stat3-interaction-in-1.html
• Purity: 90
• Smiles: O=C(C1=CC(OCCC(C)C)=CC=C1)NC2=CC=C(S(=O)(N3CCN(CC3)C)=O)C=C2
• Molecular Weight: 445.58
• References & Citations: [1]Congke Zhao, et al. Allosteric site identification, virtual screening and discovery of a sulfonamide Hsp110-STAT3 interaction inhibitor for the treatment of hypoxic pulmonary arterial hypertension. Eur J Med Chem. Q12024 Sep 7:279:116855.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported