Hsp110-STAT3 interaction-IN-1

• UNSPSC Description:

  Row174336 (compound 29) is a potent inhibitor of Hsp110-STAT3 interaction that shows antiproliferative activity against HPAEC cell line, with the IC50 of 22.67 μM[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/hsp110-stat3-interaction-in-1.html

• Purity:

  90

• Smiles:

  O=C(C1=CC(OCCC(C)C)=CC=C1)NC2=CC=C(S(=O)(N3CCN(CC3)C)=O)C=C2

• Molecular Weight:

  445.58

• References & Citations:

  [1]Congke Zhao, et al. Allosteric site identification, virtual screening and discovery of a sulfonamide Hsp110-STAT3 interaction inhibitor for the treatment of hypoxic pulmonary arterial hypertension. Eur J Med Chem. Q12024 Sep 7:279:116855.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  882582-26-5