JAK2/STAT3-IN-1

JAK2/STAT3-IN-1

• CAS Number: 2485758-50-5
• UNSPSC Description: JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].
• Target Antigen: Interleukin Related
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/jak2-stat3-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1N=C(C2=CC=C(C(F)(F)F)C=C2)C[C@H]1C3=CN(CC4=CC=C(OCCN5CCCCCC5)C=C4)C6=C3C=C(Br)C=C6)N
• Molecular Weight: 682.57
• References & Citations: [1]Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported