JAK2/STAT3-IN-1

CAT: 0804-HY-131194-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-131194-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

JAK2/STAT3-IN-1 (compound (S) -10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].

CAS Number

2485758-50-5

UNSPSC

12352005

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jak2-stat3-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N1N=C(C2=CC=C(C(F)(F)F)C=C2)C[C@H]1C3=CN(CC4=CC=C(OCCN5CCCCCC5)C=C4)C6=C3C=C(Br)C=C6)N

Molecular Formula

C34H35BrF3N5O2

Molecular Weight

682.57

References & Citations

[1]Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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