Thalidomide-PEG4-COOH

Thalidomide-PEG4-COOH

• CAS Number: 2828438-28-2
• UNSPSC Description: Thalidomide-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-peg4-cooh.html
• Smiles: O=C1N(C2C(NC(CC2)=O)=O)C(C3=CC(OCCOCCOCCOCCC(O)=O)=CC=C31)=O
• Molecular Weight: 478.45
• References & Citations: [1]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-986.
• Shipping Conditions: Blue Ice