Thalidomide-NH-PEG4-COOH

• UNSPSC Description:

  Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].

• Target Antigen:

  Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Autophagy;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/thalidomide-nh-peg4-cooh.html

• Smiles:

  O=C(C1=CC(NCCOCCOCCOCCOCCC(O)=O)=CC=C12)N(C3CCC(NC3=O)=O)C2=O

• Molecular Weight:

  521.52

• References & Citations:

  [1]Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.

• Shipping Conditions:

  Blue Ice

• CAS Number:

  2412056-48-3