(-)-5-HT2C agonist-3

• UNSPSC Description:

  (-)-5-HT2C agonist-3 (compound (–)-19) is a 5-HT2C selective agonist with Gq signaling preference, with EC50 values ??for 5-HT2 receptors of 5-HT2C: 103 nM; 5-HT2B: 570 nM; 5-HT2A: 72 nM. (-)-5-HT2C agonist-3 can be used in antipsychotic research[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/minus-5-ht2c-agonist-3.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  COC(C=CC=C1)=C1CNC[C@H]2[C@H](C3=C(C=CC(F)=C3)OC)C2.[H]Cl

• Molecular Weight:

  351.84

• References & Citations:

  [1]Guiping Zhang, et al. "Discovery of N-substituted (2-phenylcyclopropyl) methylamines as functionally selective serotonin 2C receptor agonists for potential use as antipsychotic medications." Journal of medicinal chemistry 60.14 (2017): 6273-6288.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2104810-16-2