5-HT2C agonist-3 (free base)

• UNSPSC Description:

  5-HT2C agonist-3 ((+)-19) free base is a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM). 5-HT2C agonist-3 free base has antipsychotic drug-like activity. 5-HT2C agonist-3 free base blocks Amphetamine-induced hyperactivity[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-ht2c-agonist-3-free-base.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC(C=CC=C1)=C1CNC[C@@H]2[C@@H](C3=C(C=CC(F)=C3)OC)C2

• Molecular Weight:

  315.38

• References & Citations:

  [1]Guiping Zhang, et al. Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. J. Med. Chem. 2017, 60, 14, 6273–6288.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2104810-17-3