Thalidomide-piperidine-O-Ph-NH2
CAT:
804-HY-168203
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Thalidomide-piperidine-O-Ph-NH2
- UNSPSC Description: Thalidomide-piperidine-O-Ph-NH2 is the conjugate of E3 ligase and linker. Thalidomide-piperidine-O-Ph-NH2 can be used for synthesis of PROTAC degrader MJP6412 (HY-168201)[1].
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/thalidomide-piperidine-o-ph-nh2.html
- Smiles: O=C(NC1=O)CCC1N(C2=O)C(C3=C2C=C(C=C3)N4CCC(OC5=CC=C(N)C=C5)CC4)=O
- Molecular Weight: 448.47
- References & Citations: [1]Ma M, et al., Discovery of a Highly Potent PROTAC Degrader of p300/CBP Proteins for the Treatment of Enzalutamide-Resistant Prostate Cancer. J Med Chem. 2024 Sep 29.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported