BTM-1086

• UNSPSC Description:

  BTM-1086 is a potent anti-ulcer and gastric secretory inhibiting agent.

• Target Antigen:

  mAChR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/1,5-Benzothiazepin-4_5H_-one,_2,3-dihydro-3-[_4-methyl-1-piperazinyl_methyl]-2-phenyl-,__2R,3S_-rel-.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@H](CN2CCN(C)CC2)[C@H](C3=CC=CC=C3)SC4=CC=CC=C4N1

• Molecular Weight:

  367.51

• References & Citations:

  [1]Eltze M, et al. Affinity profiles of BTM-1086 and BTM-1041 at muscarinic receptor subtypes and at H1- and alpha 1-receptors. Eur J Pharmacol. 1989 Nov 7;170(3):225-34.|[2]Hajimu Y, et al. Antiulcer Effect of (-)-cis-2, 3-Dihydro-3-(4-Methylpiperazinylmethyl)-2-Phenyl-1, 5-Benzothiazepin-4-(5H)-One Hydrochloride (BTM-1086) in Experimental Animals. Japan J Pharmacol. 41, 283-292 (1986).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  72293-17-5