LTB4-IN-1

CAT: 0804-HY-U00299Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-U00299Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC50 of 70 nM[1].
CAS Number
[133012-00-7]
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Cycloheptaneacetamide,_N-_methylsulfonyl_-_alpha_-[4-_2-quinolinylmethoxy_phenyl]-.html
Solubility
10 mM in DMSO
Smiles
O=C(NS(=O)(C)=O)C(C1=CC=C(OCC2=NC3=CC=CC=C3C=C2)C=C1)C4CCCCCC4
Molecular Formula
C26H30N2O4S
Molecular Weight
466.59
References & Citations
[1]Hatzelmann A, et al. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein. Biochem Pharmacol. 1994 Jun 15;47 (12) :2259-68.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTB4

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