LTB4-IN-2

• Description :

  LTB4-IN-2 (Comopund 6x) is a Leukotriene B4 (LTB4) inhibitor. LTB4-IN-2 inhibits Leukotriene B4 formation (IC50: 1.15 μM) by selectively targeting 5-Lipoxygenase-activating protein (FLAP) . LTB4-IN-2 can be used for anti-inflammatory research[1].

• UNSPSC :

  12352005

• Target :

  FLAP; Leukotriene Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ltb4-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N#CCC1=CC(C2=NN=C(SCC3=NC4=C(C=CC=C4)S3)N2C5=CC=CC=C5)=CC=C1

• Molecular Formula :

  C24H17N5S2

• Molecular Weight :

  439.56

• References & Citations :

  [1]Olğaç A, et al. Substituted 1,2,4-Triazoles as Novel and Selective Inhibitors of Leukotriene Biosynthesis Targeting 5-Lipoxygenase-Activating Protein. ACS Omega. 2023 Aug 18;8 (34) :31293-31304.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported