NEP-In-1

• UNSPSC Description:

  NEP-IN-1 is a neutral endopeptidase (NEP) inhibitor with IC50 of 2 nM for dNEP.

• Target Antigen:

  Neprilysin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Cyclopentanepropanoic_acid,_1-[[[3-_4-chlorophenyl_propyl]amino]carbonyl]-_alpha_-_2-methoxyethyl_-.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C(CC1(C(NCCCC2=CC=C(Cl)C=C2)=O)CCCC1)CCOC

• Molecular Weight:

  395.92

• References & Citations:

  [1]Pryde DC, et al. Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Bioorg Med Chem. 2007 Jan 1;15(1):142-59.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  465527-94-0