NEP

• Description:

  NEP (VDP-green (NEP) ) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs) . NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λex/λem=430/535 nm) . NEP has the potential for parkinsonism[1].

• Product Name Alternative:

  VDP-green (NEP)

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nep.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (N1CCCC) C2=C3C (C (NC (OCC4S[As] (SC4) C5=CC=C (C=C5) NC (CCN) =O) =O) =CC=C3C1=O) =CC=C2

• Molecular Formula:

  C29H31AsN4O5S2

• Molecular Weight:

  654.63

• References & Citations:

  [1]Guodong Hu, et al. Decrease of Protein Vicinal Dithiols in Parkinsonism Disclosed by a Monoarsenical Fluorescent Probe. Anal Chem. 2020 Mar 17;92 (6) :4371-4378.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  2414276-32-5