NEP

• Description :

  NEP (VDP-green (NEP) ) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs) . NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λex/λem=430/535 nm) . NEP has the potential for parkinsonism[1].

• CAS Number :

  [2414276-32-5]

• Product Name Alternative :

  VDP-green (NEP)

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/nep.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1CCCC)C2=C3C(C(NC(OCC4S[As](SC4)C5=CC=C(C=C5)NC(CCN)=O)=O)=CC=C3C1=O)=CC=C2

• Molecular Formula :

  C29H31AsN4O5S2

• Molecular Weight :

  654.63

• References & Citations :

  [1]Guodong Hu, et al. Decrease of Protein Vicinal Dithiols in Parkinsonism Disclosed by a Monoarsenical Fluorescent Probe. Anal Chem. 2020 Mar 17;92 (6) :4371-4378.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported