NEP (1-40)

CAT: 0931-TP1989Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TP1989Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
475221-20-6
Bioactivity
Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR) ; blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth in vitro. Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury in vivo.
Molecular Formula
C206H324N56O65
Molecular Weight
4625.16
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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