NEP (1-40)

• CAS Number :

  475221-20-6

• Bioactivity :

  Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR) ; blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth in vitro. Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury in vivo.

• Molecular Formula :

  C206H324N56O65

• Molecular Weight :

  4625.16

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C