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β-Amyloid (10-35), amide

CAT: 0804-HY-P1567Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1567Size:1 Each
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Description
β-Amyloid (10-35), amide is composed of 26 aa (10-35 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease.
CAS Number
181427-66-7
UNSPSC
12352209
Target
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_beta_-Amyloid__10-35_,_amide.html
Solubility
10 mM in H2O
Smiles
OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O
Molecular Formula
C133H205N35O36S
Molecular Weight
2902.33
References & Citations
[1]Benzinger TL, et al. Propagating structure of Alzheimer's beta-amyloid (10-35) is parallel beta-sheet with residues in exact register. Proc Natl Acad Sci U S A. 1998 Nov 10;95 (23) :13407-12.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported