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β-Amyloid (25-35)

CAT: 0804-HY-P0128-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P0128-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-Amyloid (25-35) (Amyloid beta-peptide (25-35) ) is the fragment Aβ (25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells[1].
CAS Number
131602-53-4
Product Name Alternative
Amyloid beta-peptide (25-35) ; Aβ25-35; β-Amyloid peptide (25-35)
UNSPSC
12352209
Target
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Amyloid_beta-peptide_25-35_.html
Purity
99.85
Solubility
H2O : 3.33 mg/mL
Smiles
CSCC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC(CNC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC(CNC([C@H](CCCCN)NC([C@H](CC(N)=O)NC([C@H](CO)NC(CN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C45H81N13O14S
Molecular Weight
1060.27
References & Citations
[1]D'Ursi AM, et al. Solution structure of amyloid beta-peptide (25-35) in different media. J Med Chem. 2004 Aug 12;47 (17) :4231-8.|[2]Clementi ME, et al. Abeta (31-35) and Abeta (25-35) fragments of amyloid beta-protein induce cellular death throughapoptotic signals: Role of the redox state of methionine-35. FEBS Lett. 2005 May 23;579 (13) :2913-8.|[3]Liu M, et al. Cognitive improvement of compound danshen in an Aβ25-35 peptide-induced rat model of Alzheimer's disease. BMC Complement Altern Med. 2015 Oct 23;15:382.|[4]Patel NS, et al. Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide. Amyloid. 2008;15 (1) :5-19.|[5]Julia Fedotova, et al. Ropren® is a polyprenol preparation from coniferous plants that ameliorates cognitive deficiency in a rat model of beta-amyloid peptide- (25–35) -induced amnesia. Phytomedicine. 2012 Mar 15;19 (5) :451-6.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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