UK-240455

• Description:

  UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist.

• UNSPSC:

  12352005

• Target:

  IGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/UK-240455.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CS(=O)(N(C1=C(Cl)C(Cl)=CC(NC2=O)=C1NC2=O)CCO)=O

• Molecular Formula:

  C11H11Cl2N3O5S

• Molecular Weight:

  368.19

• References & Citations:

  [1]Webster R, et al. Pharmacokinetics and disposition of a novel NMDA glycine site antagonist (UK-240,455) in rats, dogs and man. Xenobiotica. 2003 May;33 (5) :541-60.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• Isoform:

  NMDA Receptor

• CAS Number:

  [178908-09-3]