RWJ-51204

• Description :

  RWJ-51204 is a partial agonist of GABA (A) receptor, with Ki of 0.2-2 nM to the benzodiazepine site on GABA (A) receptors.

• CAS Number :

  [205701-85-5]

• UNSPSC :

  12352005

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/RWJ-51204.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C2N(COCC)C3=CC(F)=CC=C3N2CCC1=O)NC4=CC=CC=C4F

• Molecular Formula :

  C21H19F2N3O3

• Molecular Weight :

  399.39

• References & Citations :

  [1]Dubinsky B, et al. 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N- (2-fluorophenyl) carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic. J Pharmacol Exp Ther. 2002 Nov;303 (2) :777-90.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported